KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMPD2
All Species:
5.15
Human Site:
Y145
Identified Species:
10.3
UniProt:
Q01433
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01433
NP_004028.3
879
100688
Y145
S
E
L
R
S
A
P
Y
E
F
P
E
E
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093312
879
100639
Y145
S
E
L
R
S
A
P
Y
E
F
P
E
E
S
P
Dog
Lupus familis
XP_852599
799
92011
R131
G
D
R
G
L
R
E
R
D
V
V
L
E
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT5
798
92005
R131
G
D
R
G
L
W
E
R
D
V
V
L
E
R
E
Rat
Rattus norvegicus
Q02356
824
94769
D134
K
Q
D
F
L
K
T
D
S
D
S
D
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700028
819
94934
D133
M
K
T
D
S
A
T
D
L
E
Y
M
K
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727741
774
89333
L107
P
V
A
T
A
A
V
L
A
T
N
R
E
S
S
Honey Bee
Apis mellifera
XP_623550
773
88695
S105
R
R
S
H
Y
E
P
S
L
G
P
G
I
P
D
Nematode Worm
Caenorhab. elegans
NP_001040752
803
92339
L133
G
C
L
S
P
S
S
L
K
S
V
L
D
E
I
Sea Urchin
Strong. purpuratus
XP_792615
845
97202
K134
T
P
R
F
P
K
H
K
P
S
P
M
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80452
839
95111
F135
S
I
R
K
T
G
S
F
V
R
P
I
S
P
K
Baker's Yeast
Sacchar. cerevisiae
P15274
810
93283
K133
A
S
Q
N
S
G
G
K
P
R
T
L
S
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
89.5
N.A.
88.6
91.4
N.A.
N.A.
N.A.
N.A.
72.5
N.A.
52.5
54
46.8
48.3
Protein Similarity:
100
N.A.
99.8
90.2
N.A.
89.3
92
N.A.
N.A.
N.A.
N.A.
82
N.A.
67.4
65.9
60.9
63.2
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
13.3
6.6
13.3
P-Site Similarity:
100
N.A.
100
20
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
26.6
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
41.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
34
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
9
9
0
0
0
17
17
9
0
9
17
0
9
% D
% Glu:
0
17
0
0
0
9
17
0
17
9
0
17
42
17
17
% E
% Phe:
0
0
0
17
0
0
0
9
0
17
0
0
0
0
0
% F
% Gly:
25
0
0
17
0
17
9
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
9
9
0
9
% I
% Lys:
9
9
0
9
0
17
0
17
9
0
0
0
9
0
9
% K
% Leu:
0
0
25
0
25
0
0
17
17
0
0
34
9
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
9
0
0
17
0
25
0
17
0
42
0
0
17
17
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
9
9
34
17
0
9
0
17
0
17
0
9
0
17
0
% R
% Ser:
25
9
9
9
34
9
17
9
9
17
9
0
17
34
17
% S
% Thr:
9
0
9
9
9
0
17
0
0
9
9
0
0
0
9
% T
% Val:
0
9
0
0
0
0
9
0
9
17
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
17
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _